Screening for lung cancer is by and large an expensive and time-consuming process which can only be done by larger medical facilities. But Nanjing doctors now look set to change all that, with a new procedure involving just one small vial of blood.
总的来说,肺癌筛查是一个昂贵且耗时的过程,只能由较大的医疗机构来完成。但南京医生现在似乎准备改变这一切,他们推出了一种只需要一小瓶血液的新手术。
Lung cancer kills more people than any other cancer. According to the latest global cancer statistics released by the World Health Organisation in 2020, there were 9.96 million cancer deaths worldwide that year, among which 1.8 million were from lung cancer.
肺癌比任何其他癌症杀死的人都多。根据世界卫生组织发布的2020年最新全球癌症统计数据,当年全球有996万人因癌症死亡,其中180万人死于肺癌。
In fighting that, scientists and clinical experts believe that early detection, diagnosis and treatment of lung cancer are essential to prolong survival of patients, reduce economic burden and improve quality of life.
为此,科学家和临床专家认为,肺癌的早期发现、诊断和治疗对于延长患者生存、减轻经济负担和提高生活质量至关重要。
Professors Xu Lin and Yin Rong from the Jiangsu Cancer Hospital in Nanjing are among the authors of the study, “Multi-Dimensional Cell-free DNA Fragmentomic Assay for Detection of Early-Stage Lung Cancer”.
南京江苏省肿瘤医院的徐林教授和殷荣教授是该研究《用于检测早期肺癌的多维游离DNA片段组学分析》的作者之一。
Given the expensive, time consuming and, in some cases, unreliable, methods for early detection of lung cancer, the professors wondered whether there was a way that can reduce social costs, improve accuracy and have wider availability.
鉴于肺癌早期检测方法昂贵、耗时且在某些情况下不可靠,教授们想知道是否有一种方法可以降低社会成本、提高准确性并具有更广泛的可用性。
As the provincial cancer centre, Jiangsu Cancer Hospital is a quality control unit for gene sequencing, and thoracic surgery is a national key specialty.
江苏省肿瘤医院作为省级肿瘤中心,是基因测序质控单位,胸外科是国家重点专科。
Published recently by the American Journal of Respiratory and Critical Care Medicine after more than a year of critical review, the study set out to establish an accurate and affordable approach for early-stage lung cancer detection by integrating cfDNA fragmentomics and machine learning models.
经过一年多的严格审查,该研究最近由《美国呼吸与重症监护医学杂志》发表,旨在通过整合 cfDNA 片段组学和机器学习模型,建立一种准确且经济实惠的早期肺癌检测方法。
A sample pool included 350 non-cancer and 432 cancer participants.
样本库包括 350 名非癌症参与者和 432 名癌症参与者。
In a report on 10 February, Prof. Yin excitedly revealed to the Yangtze Evening News that the specificity and accuracy of their new screening method reached 90 percent through the comparative study of some cohorts.
在2月10日的报道中,尹教授兴奋地向扬子晚报透露,通过部分人群的对比研究,他们的新筛查方法的特异性和准确性达到了90%。
The professors’ research is based on the early-screening technology of liquid biopsy, using a model established by the histological characteristics of freed DNA cell fragments.
教授们的研究基于液体活检的早期筛选技术,使用根据游离DNA细胞碎片的组织学特征建立的模型。
The study’s 11 other contributing authors come from Nanjing Medical University, and Geneseeq Technology Inc. in both Nanjing and Toronto, Canada.
该研究的其他 11 位贡献作者来自南京医科大学以及南京和加拿大多伦多的 Geneseeq Technology Inc.。







